The performance and use of cyclohexanone

Date:2017-7-25 11:32:54
In the industry mainly used as organic synthesis of raw materials and solvents, for example, it can dissolve nitrocellulose, paint, paint and so on. Name: Cyclohexanone; English name: Cyclohexanone; Molecular formula: C6H10O; Molecular weight: 98.14
Compounds: aldehydes and ketones
Introduction: Carbonyl carbon atoms include saturated cyclic ketones in a six-membered ring.
Traits: colorless transparent liquid, with a soil atmosphere, containing traces of the amount of phenol, then with a mint flavor. Impurity is light yellow, with the storage time to generate impurities and color, was water white to grayish yellow, with a strong pungent odor. Mixed with air explosion limit 3.2% to 9.0% by volume, flammable and volatile. stable
Melting point: -45 ℃
Boiling point: 155.6 ° C
Flash point (open cup): 54 ℃
Relative density (20/4 ° C): 0.9478 (water = 1); 3.38 (air = 1)
Solubility: slightly soluble in water, soluble in ethanol, ether and other organic solvents. Solubility in water 10.5% (10 ℃), water solubility in cyclohexanone 5.6% (12 ℃), soluble in ethanol and ether.
Refractive index nD (20 ° C): 1.4507
Vapor pressure: 2 kPa (47 ° C), 1.33 kPa (38.7 ° C)
Viscosity: [2.2mPa · s (25 ° C)]
Self-ignition point: 520 ~ 580 ℃.
Chemical properties: same as open chain saturated ketone. Cyclohexanone in the presence of catalyst with air, oxygen or nitric acid oxidation can produce adipate HOOC (CH2) 4COOH. Cyclohexanone oxime is rearranged under the action of acid to form caprolactam. They were made of nylon 66 and nylon 6 raw materials. Cyclohexanone in the presence of alkali prone to self-condensation reaction; also easy to react with acetylene. Cyclohexanone was first obtained by dry distillation of pimelic acid. The mass production of cyclohexanone is catalyzed by phenol and then oxidized. In the industry mainly used as organic synthesis of raw materials and solvents, for example, it can dissolve nitrocellulose, paint, paint and so on.
Uses: used as synthetic resin and synthetic fiber raw materials and solvents
CAS Number: 108-94-1
Toxicity protection: high concentrations of cyclohexanone vapor are narcotic, inhibit the central nervous system. On the skin and mucous membranes have a stimulating effect. High concentration of cyclohexanone poisoning will damage the blood vessels, causing myocardial, lung, liver, spleen, kidney and brain lesions, the occurrence of large coagulation necrosis. Through the skin absorption caused by tremor anesthesia, lower body temperature, and finally to death. In the atmosphere of 25ppm irritation is small, but at 50ppm or more, it can not stand. The LC for mice was 0.008. The maximum permissible concentration of cyclohexanone in the workplace is 200 mg / m3. Production equipment should be sealed, should prevent running, running, dripping, leakage. The operator wears protective equipment.
Packaging storage and transportation: the use of iron drum, can also be used tanker transport. Storage and transportation is strictly prohibited fire and impact.
Consumption quota: raw material name specifications consumption, kg / t
1, cyclohexane process cyclohexane 99.6% 1040
2, benzene hydrogenation process benzene 99.5% 1144
Hydrogen 97.0% 1108
Liquid base 42.0% 230
Purification method: cyclohexanone is cyclohexane directly with air for catalytic oxidation or cyclohexanol dehydrogenation, the main impurities are cyclohexanol, water, adipic acid and so on. Refined with potassium dichromate sulfuric acid solution (concentration of about 5%) treatment, the cyclohexanol oxidation, and then washed with water, anhydrous sodium sulfate after drying and fractionation. High purity products can be formed with sodium bisulfite addition compounds, the same amount of adduct and sodium carbonate dissolved in hot water after the steam distillation. The distillate was saturated with salt, extracted with benzene, dried and distilled.
GB number: 33590
UN Number: 1915
Hazard Marking: 7 (Flammable Liquid)
Main use: mainly used in the manufacture of caprolactam and adipic acid, but also an excellent solvent
the effect on the environment:
The substance may be hazardous to the environment and should be given special attention to the water.
1. Health hazards Pathways: inhalation, ingestion, percutaneous absorption.
Health hazards: This product has anesthesia and stimulating effect. The skin is irritating to the skin; eye contact may cause corneal damage. Chronic effects: long-term repeated contact can cause dermatitis.
2. Toxicological information and environmental behavior
Toxicity: a low toxicity class.
Acute toxicity: LD501535mg / kg (rat oral); 948mg / kg (rabbit skin); LC5032080mg / m3, 4 hours (rats inhalation); people inhalation 300mg / m3, eye, nose, throat irritation; Inhalation 200mg / m3, feel the smell; people inhalation 50ppm, the minimum concentration of poisoning.
Irritation: human eye: 75ppm, causing irritation. Rabbit Percutaneous Open Stimulation Test: 500mg, mild irritation.
Subacute and chronic toxicity: Rabbit inhalation 12.39g / m3, 6 hours / day, 3 weeks, 4 of 2 died; 5.68g / m3, 10 weeks, mild mucosal irritation.
Mutagenicity: Microsomal mutagenesis: Salmonella typhimurium 20ul / L. Cytogenetic analysis: human lymphocytes 5ul / L.
Reproductive toxicity: Rat inhalation Minimum poisoning concentration (TCL0): 105mg / m3, 4 hours (pregnancy 1 to 20 days medication), caused by pre-implantation mortality increased. The lowest oral dose of mice (TDL0): 11g / kg (8 to 12 days of pregnancy medication), affecting the growth of newborns statistics (such as weight loss).
Carcinogenicity: IARC Carcinogenicity Comments: Animals are suspiciously positive.
Hazardous characteristics: flammable, case of high fever, open fire has caused the risk of burning. Contact with oxidant will react violently. In case of high fever, the container pressure increases, there is the risk of cracking and explosion.
Combustion (decomposition) products: carbon monoxide, carbon dioxide.
Emergency treatment and disposal methods:
1. Leakage emergency treatment Rapid evacuation of contaminated area personnel to the safe area, and isolation, strict restrictions on access. Cut off the fire source. It is recommended that emergency personnel wear self-contained positive pressure respirator and wear fire protection clothing. As far as possible cut off the source of leakage, to prevent access to sewers, drainage ditch and other restricted space. A small amount of leakage: adsorption or absorption with a sand or other incombustible material. You can also use a lot of water rinse, diluted with water into the wastewater system. A large number of leaks: build dike or digging into the shelter; with foam cover, reduce the steam disaster. With an explosion-proof pump transferred to the tanker or special collector, recycling or transported to the disposal of waste disposal sites.
2. protective measures
Respiratory protection: may be exposed to its vapor, you should wear self-absorption filter respirators (half mask).
Eye protection: Wear chemical safety glasses.
Physical protection: Wear anti-static work clothes.
Hand protection: wear anti-benzene oil gloves.
Other: work is strictly prohibited smoking. Pay attention to personal hygiene. Avoid prolonged repeated contact.
3. First aid measures
Skin contact: Remove contaminated clothing and rinse thoroughly with soap and water.
Eye contact: Immediately lift the eyelid and rinse thoroughly with plenty of water or saline for at least 15 minutes. Medical treatment.
Inhalation: quickly from the scene to the fresh air. Keep the airway open. If breathing is difficult, give oxygen. Such as breathing to stop, immediately artificial respiration. Medical treatment.
Ingestion: drink plenty of warm water, vomiting, medical treatment.
Fire extinguishing method: water spray the container, if possible, the container from the fire to the open place. Extinguishing agent: foam, carbon dioxide, dry powder, sand.